She attended Wheaton College and studied English and history. She is married to Dermot Mulroney, and has a single tike known as Clyde.

Lament stone-broke into films with 1 line around About Last Night (1986). She was nominated for an Academy Award in 2000 for her role in Existence John Malkovich however a award was given to Angelina Jolie. She likewise starred in the 2005 political thriller The Interpreter.

She guest-starred as an creative persin on an episode of Seinfeld called "The Letter". She played a artist and girlfriend of Jerry that painted the notorious portrait of Kramer [http://en.wikipedia.org/wiki/Image:The_kramer.png].

Partial filmography
Johnny Suede (1991) Out of Sight (1998) Your Friends & Neighbors (1998) 8mm (1999) Being John Malkovich (1999) Lovely & Amazing (2001) Adaptation. (2002) Death to Smoochy (2002) S1m0ne (2002) The Ballad of Jack and Rose (2005) The Interpreter (2005) The 40-Year-Old Virgin'' (2005)